Cordafen

Nifedipine

30 mg, 20 mg

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For Raynaud's Syndrome

I am 55 years of age and have primary Raynaud's. Onset was at about age 45 and for many years I just wore multiple pairs of gloves and used hand warmers when out in cold weather, or avoided cold weather activity. I finally asked my doctor about medication when it became difficult to even grocery shop in the freezer section or go to stores and restaurants that were very cool. I was tired of wearing gloves in the summer! I have taken nifedipine for about nine months (all winter) and it has been great. No side effects to report and even notice that I have a better sense of touch when feeling for pulses (I am a nurse).

General information

However, in clinical studies, concomitant nifedipine had no effect on irbesartan pharmacokinetics.
Potent CYP3A4 inducers reduce the bioavailability and efficacy of nifedipine.
Nifedipine should not be used as monotherapy unless descent is not possible and access to oxygen or portable hyperbaric therapy is not feasible.

Synonyms

Adalat
Afeditab CR

Interaction

  • This document does not contain all possible drug interactions.

Other Doses

30 mg, 20 mg
60 mg
10 mg
20 mg
90 mg
30 mg

Dosage

The night before surgery, the usual dose is 50 mg to relieve anxiety and promote sleep.
In children, the usual dose is 10mg to 20mg once a day.
Do not open, crush, or chew it.
You can take it with or without food, as desired.

Precautions

The concomitant use with corticosteroids requests caution because of an increased risk of bleeding or gastrointestinal ulceration.
CHD death, nonfatal MI, urgent coronary revascularisation after 30 days.
Dermovate is contraindicated in children under one year of age.
This combination also can cause additive negative inotropic effects.

Pregnancy

  • This drug may harm or be fatal to your unborn baby.
  • If a treatment is necessary to ensure this balance, the treatment should be started or continued at effective dose all through the pregnancy.
  • However, it is almost certainly safer to take AEDs while pregnant than to have seizures.

Avoid coadministration of nifedipine with rifampin, and consider alternative therapy if possible.

The etiology of these disorders is thought to be multifactorial and may differ between patients.186$
Dystonia: Involuntary movements and prolonged muscle contraction that result in twisting body motions, tremors, and abnormal posture.129$
The significance of the results of nonclinical studies for human risk is unknown.153.43$
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See a picture of the Heart and learn more. To decide the correct dose for you, your doctor will check your blood pressure. Estrogen containing oral contraceptives can induce fluid retention and may increase blood pressure in some patients. Erythromycin, simple CYP3A inhibitor, can inhibit the metabolism of nifedipine and increase the exposure Cordafen nifedipine during concomitant therapy.

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