75 mg, 50 mg,25 mg

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For Depression

I was prescribed imipramine for depression. It worked very well for years! BUT... it made me a diabetic with peripheral neuropathy. When I was originally given the medication I was told it would increase my appetite. It did - a LOT! It also raised my glucose levels to astronomical levels (400-500). My A1c was between 10 and 11. Over time, it damaged my nerves. I didn't realize this until my feet began to burn. After slowly decreasing imipramine by 5 mg per week until completely coming off it, my feet were unbearable. The pain was constant. I couldn't walk, or have anything on my feet. I would sleep with my blankets folded up and my feet hanging off the bed. I would soak my feet in ice water to alleviate the burning and pain.

General information

Anyone considering the use of Imipramine hydrochloride in a child or adolescent must balance the potential risks with the clinical need.




  • The clinical importance of these interactions is uncertain.

Other Doses

75 mg, 50 mg,25 mg
12.5 mg/mL
50 mg
pamoate 150 mg
pamoate 100 mg


This medication may be used to treat high blood pressure, as a vasodilator in the treatment of heart failure and as adjunctive treatment of chronic kidney failure.
Nicotine is delivered to the brain through smoking, chewing, or sniffing tobacco.
Two of 16 reports list doses higher than the licenced daily limit.
The tablet is usually taken two or three times a day with food.


Thyroid hormone increases the metabolic rate of cells of all tissues in the body.
If taken with alcohol, however, it alters certain steps in the breakdown of alcohol.
Therefore, this medication should be used at the lowest effective dose and for the shortest amount of time.


  • For this reason pregnant patients should be given Vitamin K1 through the last month of pregnancy up to the time of delivery.
  • This infection can lead to problems in getting pregnant.
  • Extensive epidemiological studies have revealed neither an increased risk of birth defects in children born to women who used COCs prior to pregnancy, nor a teratogenic effect when COCs were taken inadvertently during early pregnancy.
  • Exposure to pyrethrins should be minimized in pregnancy.
  • Data from epidemiological studies suggest an increased risk of miscarriage and of cardiac malformation and gastroschisis after use of a prostaglandin synthesis inhibitor in early pregnancy.

To resolve this, drink a mouthful of water before taking sublingual tablets.

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