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Zoloft (sertraline) for Panic Disorder

After 1 week of loose bowels and strange stomach noises/sensations, week 2 came and the jaw clenching/teeth grinding sensation in my temples started. Along with throat pain and suicidal thoughts, it was tough to stick it out and stay on but I did. I started on 25mg then up to 50mg then on to 75mg by week 3. Things got better around then. I still felt anxious, but the medicine was blocking my physical response that my body would produce from stress and anxiety. I would get chest pains, stomach pains, head pains all the time, got checked out by every specialist under the sun, and I'm a healthy 31 year old man with normal or better than normal heart, brain, lung and organ function. It was all in my head and Zoloft stopped my suffering.

General information

Hi all, I have been on sertraline for 18 months and decided 4 weeks ago to gradually come off it.
Sertraline is a prescription medication used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, post traumatic stress disorder, social anxiety disorder and premenstrual dysphoric disorder.




  • Speak to your doctor about how any drug interactions are being managed or should be managed.

Other Doses

100 mg, 50 mg, 25 mg
25 mg
20 mg/mL
100 mg
50 mg


When taken orally, absorption of this form is drastically reduced if you have any gastric acid problems.
The schedule may be adjusted gradually to achieve an optimal response but should not exceed a total weekly dose of 20 mg.
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  • If you get pregnant while taking this drug, tell your doctor right away.
  • There may be other medicines to treat your condition that have a lower chance of causing birth defects and decreased IQ in your child.
  • When accidental treatment has occurred during pregnancy, therapy should be immediately changed to one of the recommended antihypertensive agents.
  • Medicines should not be used in pregnancy, especially in the first trimester, unless the expected benefit is thought to outweigh the possible risk to the foetus.

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It is believed that some illnesses such as depression are caused Lustramerck disturbances in the balance between serotonin and other neurotransmitters. Zoloft by reducing the elimination of Zoloft by the liver. This is not a complete list of side effects and others may occur.


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