For Psoriasis

At age 66, after a very stressful phase of work over 7 months, I developed psoriasis very suddenly. With no previous skin problems & no family history of psoriasis either, I conclude that the stress was the trigger. I had the psoriasis all over but the worst was on my scalp - it felt like an iron band pressing in around my head. The dermatologist prescribed a whole range of creams and ointments over a year. Nothing worked. Finally in Nov. 2015 I was proscribed methotrexate + 1 folic acid tablet weekly. I was told it would take up to 3 months to kick in & it did, but in Aug.'16 I am virtually clear with no side-effects. The dosage has increased to 15 mg weekly & all my blood tests are normal. But will I have to stay on methotrexate for life?

General information

However, the precautionary approach is to limit or avoid breast feeding in mothers being treated with methotrexate.
Understand the side effects of methotrexate and how you can take measures to keep them to a minimum.
If you are taking methotrexate to treat rheumatoid arthritis, it may take 3 to 6 weeks for your symptoms to begin to improve, and 12 weeks or longer for you to feel the full benefit of methotrexate.
You should store methotrexate in the original container that it came in.

Synonyms

Rasuvo

Interaction

• Despite the potential interactions, studies of methotrexate in patients with rheumatoid arthritis have usually included concurrent use of constant dosage regimens of NSAIDs, without apparent problems.

Other Doses

2.5 mg
27.5 mg/0.55 mL
50 mg
20 mg
1 g
30 mg/0.6 mL
10 mg

Dosage

Keep using the medication as directed and call your doctor promptly if this medicine seems to stop working as well in preventing your seizures.

Avloclor should be taken each week on the same day each week.

The extent to which this interaction is clinically relevant depends on the dose and route of administration of the corticosteroids and the potency of the CYP3A4 inhibitor.

To help you remember, take this medication at the same time every day.

Precautions

Exclusion criteria included having comorbid diagnoses with major depression, marked anxiety or history of bipolar depression or psychosis, major physical illness, alcohol abuse, active use of illicit drugs, or having an IQ of less than 75.
The incidence of serious adverse reactions was comparable in all trials.
Taking certain products together can cause you to get too much of this type of medication.
COCs also do not indicate an increased risk.

Pregnancy

• Both of these are important for both you and your baby.
• Extreme care must be taken to avoid pregnancy in female patients.
• Serevent should be used only when prescribed during pregnancy.
• If you take Depakote or Depakene during pregnancy for any medical condition, your child is at risk for having a lower IQ.

This medication may also be used for lupus and psoriatic arthritis.

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Johnson syndrome, skin necrosis, exfoliative dermatitis, epidermal necrolysis. In dogs, synovial fluid concentrations after oral dosing were higher in inflamed than uninflamed joints. Methotrexate monitoring form to be used as part of the patient record.

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